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Testing a home-based model of care using misoprostol for prevention and treatment of postpartum hemorrhage: results from a randomized placebo-controlled trial conducted in Badakhshan province, Afghanistan

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Authors: Dina F. Abbas, Shafiq Mirzazada, Jill Durocher, Shahfaqir Pamiri, Meagan E. Byrne, and Beverly Winikoff

In Afghanistan, where a majority of births take place outside of a formal healthcare system and without a skilled health professional, postpartum hemorrhage (PPH) is a high risk. The authors of this study conducted a randomized-controlled trial to determine the effectiveness of a prophylactic drug, misoprostol, on treating PPH. Community health workers (CHWs) identified cases of PPH and administered the medication. The results showed insufficient evidence to support a clinical benefit of CHW-delivered misoprostol; however, there is promise for the drug to act as both a prevention method and a treatment course for PPH.

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Link: Testing a home-based model of care using misoprostol for prevention and treatment of postpartum hemorrhage: results from a randomized placebo-controlled trial conducted in Badakhshan province, Afghanistan

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Resource Topic: Community Health Workers/Volunteers, Maternal, Newborn and Child Health, Postpartum Health

Resource Type: Research

Year: 2020

Region: Asia

Country: Afghanistan

Publisher May Restrict Access: No

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