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Prevalence of onchocerciasis and epilepsy in a Tanzanian region after a prolonged community-directed treatment with ivermectin

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Authors: Vivian P. Mushi, Dan Bhwana, Isolide S. Massawe, Williams Makunde, Hillary Sebukoto, Willison Ngasa, Joel Sengerema, Athanas Mhina, Paul M. Hayuma, Henrika Kimambo, Winifrida Kidima, William Matuja, Josemir W. Sander, Helen Cross, Arjune Sen, Robert Colebunders, Charles R. Newton, Bruno P. Mmbando , EPInA Study Group

A study conducted in Mahenge, Tanzania, aimed to assess the prevalence of onchocerciasis and epilepsy after 25 years of ivermectin treatment. Community health workers (CHWs) played a key role by conducting door-to-door household surveys, screening individuals for epilepsy, and helping with onchocerciasis testing. The study found that 11.8% of children tested positive for onchocerciasis, with higher prevalence in villages at medium altitudes. Epilepsy was present in 21.1 per 1000 people, with an increased risk in females, those living at medium altitudes, and individuals testing positive for onchocerciasis antibodies. Despite long-term ivermectin use, both onchocerciasis and epilepsy rates remain high, highlighting the need for enhanced treatment and vector control interventions. CHWs were essential in identifying and reaching vulnerable populations, making healthcare more accessible in rural areas.

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Resource Topic: Epilepsy

Resource Type: Evaluation

Year: 2024

Region: Sub-Saharan Africa (SSA)

Country: Tanzania

Publisher May Restrict Access: No

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