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Effectiveness of a Home-based Approach to Child Contact Investigation and TPT Management by Community Health Workers in Ethiopia: A Pragmatic Cluster-randomized Trial

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Authors: Nicole Salazar-Austin, Silvia Cohn, Bareng A S Nonyane, Christiaan Mulder, Fiseha Mulatu, Samuel Bayu, Moges Bizuayehu, Gidea Conradie, Akash Malhotra, Paul Phan, Natalia Hernandez Morfin, Stephanie Borsboom, Petros Mitiku, Demissu Fulas, Mulunesh Tulema, Jonathan E Golub, Richard E Chaisson, Gavin Churchyard, Ahmed Bedru

This study in Ethiopia tested if giving tuberculosis (TB) prevention treatment to children at home works better than the usual clinic-based approach. Community health workers visited homes to manage care. The results showed that 40% more children started treatment when care was given at home. Most children in both groups finished treatment, and side effects were rare. The home-based approach helped reach more children and could be a useful way to prevent TB in other places too.

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Resource Topic: CHW, Tuberculosis

Resource Type: Randomized controlled trial

Year: 2025

Region: Sub-Saharan Africa (SSA)

Country: Ethiopia

Publisher May Restrict Access: No

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