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Association of clinical signs of possible serious bacterial infections identified by community health workers with mortality of young infants in South Asia: a prospective, observational cohort study

February 14, 2025 By

Authors: Gary L. Darmstadta ∙ Saifuddin Ahmedb ∙ Mohammad Shahidul Islamc ∙ Safa Abdallaa ∙ Shams El Arifeend ∙ Melissa L. Arvaye ∙ Abdullah H. Baquif ∙ Zulfiqar A. Bhuttag,h ∙ Anuradha Bosei ∙ Nicholas E. Connorj ∙ Belal Hossainb ∙ Rita Isaaci ∙ Arif Mahmudf ∙ Dipak K. Mitraf ∙ Luke C. Mullanyf ∙ Imran Nisark ∙ Kalpana Panigrahil ∙ Pinaki Panigrahim ∙ Qazi Sadeq-ur Rahmand ∙ Senjuti Sahac ∙ Sajid B. Soofik ∙ Nardos Solomona ∙ Mathuram Santoshamf ∙ Stephanie J. Schrage ∙ Shamim A. Qazin ∙ Samir K. Saha

This study aimed to understand how certain signs in young infants, like poor feeding or lack of movement, can predict the risk of death. Community health workers (CHWs) in Bangladesh, India, and Pakistan visited infants regularly to check for these signs. The study found that signs like no movement, poor feeding, and low body temperature were strongly linked to a higher risk of death. The highest risk was seen in infants who had no movement or only moved when stimulated. The study suggests that hypothermia, in particular, should be reconsidered as a sign of serious illness and calls for better ways to help infants early by referring them for care in areas with fewer resources.

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Resource Topic: CHW Role, Child Care, Child health, Integrated Community Case Management/iCCM

Resource Type: Cohort Study

Year: 2025

Region: Asia

Country: Bangladesh, India, Pakistan

Publisher May Restrict Access: No

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