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“We might have been prescribing antibiotics to clients who do not need them”: a mixed-methods study of knowledge, attitudes, and practices related to antibiotic use for pediatric acute respiratory illness among community health workers in Uganda

November 11, 2025 By

Authors: Emily J Ciccone, Ana T Bravo Gutierrez, Grace Nyangoma, Victoria Shelus, Georget Kibaba, Fred Mwebembezi, Emmanuel Baguma, Raquel Reyes, Jonathan J Juliano, Ross M Boyce, Moses Ntaro, Edgar M Mulogo

This mixed-methods study in rural Uganda assessed Community Health Workers’ (CHWs) practices regarding antibiotic use for pediatric Acute Respiratory Illness (ARI). While CHWs were knowledgeable about antibiotics, they recognized that the standard ICCM diagnostic algorithm relying on breathing rate likely contributes to overuse. Training on an enhanced ICCM  algorithm (STAR SCJA) that included a C-reactive protein (CRP) test led to a major shift in CHW prescribing practices. CHWs strongly favored the enhanced algorithm, feeling it improved treatment accuracy and confidence. The research concludes that CHWs are an underutilized resource for Antimicrobial Stewardship (AMS).

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Resource Topic: Antimicrobial resistance, CHW Role, Child Care

Resource Type: Mixed Methods

Year: 2025

Region: Sub-Saharan Africa (SSA)

Country: Uganda

Publisher May Restrict Access: No

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